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Filtered Search Results
Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000569671 SIVELESTAT-SODIUM-SALT-10MG
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000588105 PHOSPHO-SYK TYR525/526 C87C1 R
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Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3980306 AMMONIUM FORMATE SOLUTION 10MM
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Medchemexpress LLC Dids sodium salt | 67483-13-0 | 99.1% | 5 MG
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DIDS sodium salt (MDL101114ZA) is a dual inhibitor of ABCA1 and VDAC1. It also inhibits RAD51, specifically RAD51-mediated homologous pairing and strand exchange reactions. DIDS inhibits anion exchange and binding to red blood cell membranes, inhibits the activation of caspase-3 and -9, and can be used in cancer research.
- Dual inhibitor of ABCA1 and VDAC1
- Inhibits RAD51-mediated homologous pairing and strand exchange reactions
- Inhibits anion exchange and binding to red blood cell membranes
- Inhibits the activation of caspase-3 and -9
- Can be used in cancer research
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AdipoGen Ganglioside GM1 Na bovine
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Chemical. CAS 37758-47-7. Formula C73H130N3O31 . Na. MW 1545.8 . 23.0 calculated on sphingosine C181 and stearic acid. Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GM1 is a major sialoglycolipid of neuronal membranes that modulates calcium homeostasis and which is important for neuronal plasticity and repair mechanisms. It binds to cholera toxin B subunit, resulting in stimulation of adenylyl cyclase in a wide variety of cell types.
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Apexbio Technology LLC Rigosertib sodium salt 1225497-78-8 25mg
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Rigosertib sodium salt (CAS 1225497-78-8) is a selective inhibitor targeting Polo-like kinase 1 (PLK1) with reported IC50 approximately 9 nM The compound notably decreases proliferation of cancer cell lines demonstrating nanomolar IC50 values in HeLa (115 nM) and C33A (45 nM) cells whereas normal cells (e g BJ and Ect1/E6E7) remain largely unaffected At concentrations exceeding 0 5 M rigosertib robustly induces G2/M phase arrest in cancer cells without significant cell cycle disruption at lower doses Additionally in vivo studies suggest its potential as a radiosensitizer in cervical carcinoma research
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Sigma Aldrich Fine Chemicals Biosciences dGTP PCR Grade sodium salt
dGTP PCR Grade is a 100 mM clear colorless SOLUTIONon of the sodium salt (pH 8.3). PCR Grade nucleotides from Roche are specially manufactured and purified to the highest possible chemical purity. PCR Grade nucleotides contain at least 99% of the relevant deoxynucleoside-triphosphate (dNTP) and less than 0.9% deoxynucleoside-diphosphate (dNDP).
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Chem-Impex International, Inc. Ammonium formate | 540-69-2 | MFCD00013103 | 5KG
Ammonium formate, 540-69-2, MFCD00013103, 5KG
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AdipoGen Diazidostilbenedisulfonic acid
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Chemical. CAS 2718-90-3. Formula C14H8N6Na2O6S2 . 4H2O. MW 538.42. Synthetic. A reagent for enzyme immobilisation on fibroin by photo-crosslinking. The reagent is water-soluble over a wide pH range.
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Selleck Chemical LLC Taurocholic acid sodium salt
Taurocholic acid sodium salt (Sodium Taurocholate TANa) is a sodium salt of taurocholic acid and occurs in the bile of mammals Taurocholic acid is used as a cholagogue and choleretic
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Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 10mg
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AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
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Apexbio Technology LLC Cefazolin (sodium salt) 27164-46-1 500mg
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Cefazolin sodium salt (CAS 27164-46-1) is a semisynthetic antibiotic that inhibits bacterial cell wall synthesis by binding to specific penicillin-binding proteins thereby blocking transpeptidation reactions essential for peptidoglycan formation In in vitro studies cefazolin sodium salt suppresses the proliferation of cultured osteoblast-like MG-63 cells exhibiting substantial cytotoxicity at concentrations of 10 000 g/ml precise IC50 values depend on cell type and experimental conditions Cefazolin sodium salt is commonly used in microbiology pharmacokinetic investigations and infection models particularly within studies of antimicrobial susceptibility and renal dysfunction
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Apexbio Technology LLC Rigosertib sodium salt 1225497-78-8 10mM (in 1mL DMSO)
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Rigosertib sodium salt (CAS 1225497-78-8) is a selective inhibitor targeting Polo-like kinase 1 (PLK1) with reported IC50 approximately 9 nM The compound notably decreases proliferation of cancer cell lines demonstrating nanomolar IC50 values in HeLa (115 nM) and C33A (45 nM) cells whereas normal cells (e g BJ and Ect1/E6E7) remain largely unaffected At concentrations exceeding 0 5 M rigosertib robustly induces G2/M phase arrest in cancer cells without significant cell cycle disruption at lower doses Additionally in vivo studies suggest its potential as a radiosensitizer in cervical carcinoma research
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Medchemexpress LLC E7766 diammonium salt | 2242635-03-4 | 99.5% | 780.66 | C24H32F2N12O8P2S2 | 5 MG
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E7766 diammonium salt is a macrocycle-bridged stimulator of interferon genes (STING) agonist that binds STING with high affinity (Kd ≈ 40 nM) and has shown potent pan-genotypic activation and antitumor efficacy in preclinical studies. The compound is supplied as the diammonium salt for research applications and is provided at high reported purity with recommended frozen storage to preserve stability.
- Macrocycle-bridged STING agonist with high affinity (Kd ≈ 40 nM).
- Demonstrated pan-genotypic STING activation and antitumor activity in preclinical models.
- Supplied as a diammonium salt with high purity (≈99.5%).
- Molecular weight 780.66 g·mol-1; formula C24H32F2N12O8P2S2.
- Recommended storage at -20°C to maintain stability for research use.
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Cambridge Isotope Laboratories Glufosinate ammonium salt (unlabeled) 100 ug/mL in water 1 2 mL
Glufosinate ammonium salt (unlabeled) 100 ug/mL in water 1 2 mL
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